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For instance, using the CRISPR/Cas9 system to edit genes in human pluripotent stem cells, organoids can be generated to model autosomal dominant polycystic kidney disease (ADPKD), enabling the study of cyst formation and related pathological mechanisms ( In drug nephrotoxicity studies, kidney organoids can replicate histological characteristics similar to natural kidneys in models of acute renal tubular injury induced by cisplatin

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Endurance athletes are especially vulnerable because intense exercise depletes natural glutathione levels, slowing recovery and taxing the immune system

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In brief, cells were lysed in an adequate volume of TRIzol reagent and chloroform according to the instructions of the manufacturer

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Food-derived Hydrophilic Antioxidant Ergothioneine Is Distributed to the Brain and Exerts Antidepressant Effect in Mice

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375 HSP27 modulators HSP27 modulation has also shown therapeutic promise

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