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Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice
It incorporates a drug affinity complex (DAC), which is thought to extend its presence in circulation by associating with plasma proteins
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This is particularly beneficial for adults over 65 and those with problems or previous surgery in the digestive tract
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43.8% of YHV984 was released from the particles within 6 h, followed by a slow-release phase, with more than 80% release achieved after 48 h
