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In the head to head SURMOUNT-5 trial, tirzepatide produced a mean weight reduction of 20.2 percent at 72 weeks compared with 13.7 percent for semaglutide

If your shedding is persistent, worsening, or comes with patchy loss or scalp symptoms, a professional evaluation can help clarify what is really driving it

This pattern reflects the underlying biology rather than treatment failure

Hormonal Balance & Cluster Symptoms

Researchers who add too many variables simultaneously cannot identify which compound is producing which effect, making troubleshooting impossible

Recovery typically requires 6 to 12 months before return to running