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Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583)

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A common protocol, for example, is to begin with about 20 mg of NAD+ (corresponding to a small volume from the vial, typically around 0.1 mL depending on concentration) administered subcutaneously and gradually increase the dose over subsequent injections up to around 100 mg per injection