It is important to note that the causal role of ferroptosis is supported by interventional studies: in mouse models, the ferroptosis inhibitor Ferrostatin-1 (Fer-1) was shown to alleviate testicular damage and improve sperm quality, confirming its status as a key pathogenic mechanism ( Ferroptosis has also been implicated in other common causes of male infertility, including asthenospermia and varicocele
Inflammaging is associated with increased susceptibility to infections, autoimmune disorders and various age-related diseases, creating a feedback loop that accelerates the breakdown of immune health and increases morbidity and mortality risks among elderly [3, 4]
A study published in the esteemed journal Nature explored how a high-fat diet or obesity induced through genetic means impacted hair loss in mice
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Gut hormone co-agonists for the treatment of obesity: from bench to bedside
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