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Current pharmacological strategies for UC primarily include 5-aminosalicylic acid (5-ASA), glucocorticoids, thiopurines, biological medications, and anti-cytokine therapies (Lamb et al., 2019
Detoxification occurs in two phases
To put that in perspective: if your therapeutic dose is 500 mcg, you'd theoretically need 500,000 mcg (500 mg) to approach potentially toxic levels
Administration: Delivered directly into the bloodstream via an IV drip, bypassing the digestive system entirely
This is due to cumulative damage to mitochondrial DNA which would otherwise have been reduced by glutathiones antioxidant activity and protective effects
For instance, pairing subcutaneous injections with topical products or microneedling can maximize both systemic and localized benefits for skin and hair
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