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Across phenotypes, our data indicate an association between rs1800437 and tirzepatide treatment for both the vomiting and nausea phenotypes, and potentially constipation, but the variant does not seem to influence efficacy ( P = 0.73
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These trials were not focused on dermatological safety, so only general side effects were noted
Sanger Sequencing Direct Sanger sequencing for BRAF V600E mutation was done by SinoMD Gene Technology Co
Side effects: Most patients have no significant side effects
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