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TB-500 is a synthetic fragment of thymosin beta-4 (residues 1723, sequence Ac-LKKTETQ) studied for its role in actin sequestration and cytoskeletal organization specifically the regulation of G-actin to F-actin polymerization balance that governs cell morphology and migration
US Department of Transportation, Office of Drug and Alcohol Policy and Compliance
Reference: Wound Healing Tripeptide Review (2025)
Chen, I.-T., Hsu, P.-H., Hsu, W.-C., Chen, N.-J
Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced