glp-1 medication long term side effects Understanding the Long-Term Impact of Meds on Digestive Health Do The Benefits of GLP-1

Gastrointestinal effects and referred pain: The pronounced gastrointestinal side effects of GLP-1 therapyparticularly nausea, constipation, and abdominal distensioncan occasionally manifest as referred pain to the back

On the one hand, a 2020 pilot study showed that increased growth hormone circulation could preserve quadriceps strength in patients whod undergone reconstructive surgery after an anterior cruciate ligament injury;18 on the other, an in vitro study from 2024 found that growth hormone administered to tendon and ligament cells [did] not appear to positively affect cellular proliferation and differentiation.19 More research is needed before we can say for sure whether CJC-1295, ipamorelin, and similar peptide treatments have dependable utility toward injury recovery

In December 2024, a phase IIa dose-ranging trial (NCT06717425 ) to investigate this drug began, and is due to end in December 2025 5

There are no regulatory approvals as yet to support the prescribing of GLP-1s to pouchees per se only to people with diabetes and/or obesity (whether or not they have a pouch)

2020 Sep;53(6):35361

Strength training changes your metabolism even when you're resting