It might not be safe for people with: Allergies to vitamin B12 Lebers disease, which affects eyesight Kidney issues Low potassium levels Not having enough other important nutrients like folic acid and iron
The American Journal of Clinical Nutrition
In PA patients the parietal cells that produce intrinsic factor is destroyed due to an autoimmune reaction that also leads to an atrophic gastritis
Direct impact can shear peptide bonds through mechanical force, damaging the compound before it even dissolves
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[4] Solid tumours: Certain cancers, particularly hepatocellular carcinoma, pancreatic cancer, and metastatic disease, may elevate B12 through various mechanisms