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Researchers measure insulin, C-peptide, and glucagon release by ELISA, and assess islet gene expression using RNA sequencing or targeted qPCR panels to characterize transcriptional responses to prolonged GLP-1R activation

Because postmenopausal women on hormone therapy combined with GLP-1s often achieve significantly greater weight loss than those on GLP-1s alone, AI models could track symptoms alongside metabolic markers and help determine the optimal dosage of the GLP-1 to use in conjunction with hormone therapy, maximizing the benefit of both

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