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Our research study faced limitations primarily due to the high heterogeneity among included studies and the relatively low number of articles in our meta-analysis
Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales
[12] The therapeutic application of melatonin extends beyond primary sleep disorders to include potential benefits in managing sleep disturbances associated with neurodevelopmental conditions, neurodegenerative diseases, and certain psychiatric disorders
The failure of both Pfizer oral GLP-1 candidates underscored the difficulty of the small-molecule approach and left orforglipron as the only advanced oral non-peptide GLP-1 agonist in clinical development
A novel target for next-generation obesity medications is nicotinamide N-methyltransferase (NNMT) 7,8,9,10,11 , an enzyme central to cellular metabolism and energy homeostasis 12
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