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Supplementary Table 13 (download XLSX The potencies of peptides designed in this study by the multi-task neural-network ensemble model against human GLP-1R were measured in triplicate, in three independent measurements

Semaglutide often causes mild nausea, bloating, or constipation as the body adjusts

As with any pharmaceutical product, GLP-1 agonists should not be depended upon as the sole agent to achieve weight loss, but rather viewed as an adjunct to other treatment modalities nutrition, physical activity, sleep, etc

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only 9% of placebo-treated patients, achieving statistical significance ( P = 0.019)