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In biochemical and cellular systems MT-II acts as a broad, non-selective agonist across the melanocortin receptor family MC1R, MC3R, MC4R and MC5R with negligible activity at MC2R

8,14,15 Although most approved GLP-1RAs and co-agonists have not yielded satisfactory results in histological endpoint clinical trials, the future of managing and treating MASLD holds promise

Understanding whether a minimal dose can sustain results requires examining both clinical evidence and your unique peptide pathway activation

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Seiwerth, S., Brcic, L., Vuletic, L

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