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CONTRAVE (naltrexone/bupropion) is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off
If heart rate increases are problematic at a particular dose level, discuss with your physician whether maintaining that dose longer before escalation, or potentially remaining at a lower maintenance dose, might be appropriate
These abnormalities may be due to both acquired and genetic factor ,
Most established programs continue to operate under the patient-specific pathway
In the event of a missed dose, it should be taken promptly upon recollection unless nearing the time for your next scheduled administration