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The most clinically relevant Z variant of AAT protein differs from the normal M by a single amino acid substitution (Glu342Lys)
Cells were subjected to treatment in incubator for 24 hr
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In the absence of the cluster, such monothiol glutaredoxins can still be glutathionylated 26,27,29 and might (slowly) transfer the glutathione moiety to reduced cysteine residues as suggested for the AtGrxS15-dependent oxidation of reduced roGFP2 by GSSG
AOD-9604 is a modified C-terminal fragment (residues 176191, Tyr-hGH177-191) of human growth hormone, studied for lipolytic and anti-obesity properties
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