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It was first characterized by Raun et al
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However, it is most often produced in the liver, in which the vital substance plays a central role
Purine-based intervention All reviewed studies [86,87,88] reveal a consistent pattern of findings
Muscle protein is in a constant state of turnover, meaning that protein synthesis is occurring continuously to replace protein lost as a consequence of protein breakdown
A liver biopsy was obtained and immediately frozen
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