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Novo Nordisk on Friday released headline data from the Phase III REDEFINE 1 trial of its next-generation weight-loss therapy CagriSema, touting superior weight loss in people with obesity and overweight than just cagrilintide, semaglutide (marketed as Wegovy for weight loss and Ozempic for diabetes) or placebo
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They also didn't eat more when they stopped getting nicotine
People who use the appetite suppression as an opportunity to improve dietary quality, choosing nutrient-dense foods , adequate protein, and appropriate fiber, tend to see better and faster results than those who simply eat smaller portions of the same calorie-dense foods
At the same time, their well-documented effects on gut motility raise reasonable questions about digestive health, especially for individuals with IBS, a history of food poisoning, constipation, or other risk factors for microbial overgrowth
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