Pruritus accompanied by jaundice (yellowing of skin or eyes), dark urine, or light-colored stools could indicate gallbladder or liver complications and requires prompt evaluation with appropriate testing
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Overall, in addition to serving as a carbon skeleton source to replenish the TCA cycle, Gln metabolism supports TCA cycle anaplerosis and OXPHOS while providing key intermediates such as -KG, thereby participating in metabolism-epigenetic coupling and influencing the positioning of macrophages along the pro-inflammatory to reparative functional spectrum ( 4.4 Branched-chain amino acids Branched-chain amino acids (BCAAs