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Vascular factors may be the most critical of all

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At the 12mg dose, more than 90% of participants lost at least 10% of their body weight, and roughly 75% lost at least 15%

Secondary outcomes showed improvements in oxygen saturation parameters, sleep quality measures, and patient-reported outcomes related to daytime functioning and quality of life

Regarding thyroid safety, rodent studies have shown C-cell tumours, though the relevance to humans remains unknown

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