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Excess weight and uncontrolled blood sugar are major risk factors for heart disease, stroke, hypertension, and early onset metabolic conditions

Mason AE, Daubenmier J, Moran PJ, Lustig RH, Dallman MF, Acree M, Bacchetti P, Laraia B, Brown R, Hecht FM, Epel ES: Reduced reward-driven eating accounts for the impact of a diet and exercise intervention with mindfulness training on weight loss: data from the SHINE randomized controlled trial

The challenge is distinguishing semaglutide's direct neurological effects from indirect benefits of weight loss and improved metabolic health

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Chern YJ, Tai IT

Svendsen B, Pedersen J, Albrechtsen NJW, Hartmann B, Torng S, Rehfeld JF, et al