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Overcoming the Shortcomings of Peptide-Based Therapeutics

The peptide sequence, derived from human growth hormone, appears sufficiently similar to native proteins that the immune system does not mount a response against it

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Top-selling drug charts in 2025H1 show GLP-1 agonists displacing traditional blockbusters, reflecting how obesity and diabetes treatments have become huge revenue drivers

Moreover, VK2 suppresses the MAPK/NF-B axis, resulting in decreased production of MMP3 and MMP13, while enhancing the synthesis of type II collagen and proteoglycans, so collectively mitigating ECM breakdown [114]