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Randomization was stratified according to country, sex (female, male) and per cent weight reduction at the end of lead-in ( 90% to demonstrate the superiority of tirzepatide MTD to placebo, for the coprimary endpoints, each at a two-sided significance level of 0.05

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Despite the apparent compliance with meat restriction, metabolomic analysis identified marked elevations of TMAO in the majority of patients with an organic acidemia (Fig

Think about it like blood pressure drugs, Azagury said

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Why do they still seem uncertain, or quiet, or not quite themselves