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Studies from in vitro experiments have shown that the Keap1/Nrf2 and PINK1/Parkin pathways together play critical roles in neuroprotection by synergistically regulating antioxidant responses and mitochondrial quality control

Xenografted human amniotic membrane-derived mesenchymal stem cells are immunologically tolerated and transdifferentiated into cardiomyocytes

v-ATPase-induced shifts in pH may function as a signaling cue triggering broader metabolic reprogramming, such as nutrient sensing at the lysosome, and may phenocopy a nutrient-deprived or energy-stressed state, even in the presence of external nutrients 42

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