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For patients at high risk of cardiovascular events particularly those with established atherosclerotic disease current guidelines from the ADA and ESC now favour GLP-1 receptor agonists as a preferred second-line therapy after metformin

No Stress Hormone Spike: Unlike GHRPs, it avoids cross-reactivity with receptors that trigger cortisol or prolactin, preventing catabolic side effects

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Blood sugar tends to settle as well, without the nightly dip that alcohol can bring on top of the medication

Reference: FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway

We have treated adult patients with growth hormone deficiencies as young as 30 and as old 93