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Plateau Discussion May be relevant for clients asking what comes after semaglutide or tirzepatide
147 Reddy A, Dash C, Leerapun A, Mettler TA, Stadheim LM, Lazaridis KN, et al
Efficacy Comparison Table Clinical trial data from the PIONEER program (Rybelsus) and SURPASS program (Mounjaro) provide a lot of evidence for comparing these medications: Mounjaro dominates across glycemic control and weight loss metrics, while Rybelsus leads with proven cardiovascular data from the SOUL trial
This was observed among participants in the high-dose group
Understanding the specific effects reported helps set realistic expectations and allows for informed monitoring during treatment protocols
Aggressive (postoperative): 1000 mcg/day during Weeks 12
