- Eva Madrid, co-lead researcher from Universidad de Valparaso, Chile
Currently, large-scale production of the pigments is achieved through extraction from plant raw materials with high contents of stable anthocyanins ( 1 ), for example, purple sweet potato, black carrot or red cabbage 5 , despite the associated issues of sustainability and supply
GSTs are multifunctional enzymes that catalyze the conjugation of glutathione (GSH) to electrophilic compounds, including xenobiotics and reactive oxygen species (ROS), converting these into less toxic metabolites for excretion 49
Doxorubicin was selected as a training compound for three reasons: i) the quinone moiety, present in doxorubicin, is acknowledged as a notorious redox cycler
We recently showed that hepatic SLC39A14 accelerates iron-induced ferroptosis in the liver of hepatic Trf knockout mice via its ability to transport NTBI, revealing a novel molecular mechanism by which ferroptosis drives the pathogenesis of liver fibrosis and cirrhosis [26]
Applicable medical director, supervision, delegation and scope-of-practice requirements, including any state-specific practice guidance specifically related to these issues