[90] In March 2026, the CHMP recommended granting a conditional marketing authorization for Kayshild (semaglutide), a GLP-1 receptor agonist for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with liver fibrosis, a serious disease where fat deposits accumulate in the liver causing inflammation
It must be the same drug chemically and have the same medical effect
Despite not being required by the drugs Risk Evaluation and Mitigation Strategy (REMS), regular liver enzyme monitoring is recommended [107]
concluded in 2024: "We do not recommend the use of BPC-157 for sports performance and recovery because there are no randomized controlled trials in human subjects
Finally, the increasing off-label use of GLP-1 RAs for weight loss in non-diabetic individuals may further exacerbate access limitations and drug shortages, potentially disadvantaging patients with T2DM
Reducing protein intake in geriatric cats, at a time when lean tissue has been lost, is contraindicated