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CR6-interacting factor 1 (CRIF1) regulates NF-E2-related factor 2 (NRF2) protein stability by proteasome-mediated degradation

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The ZIP family facilitates the influx of zinc into the cytosol from either the extracellular space or intracellular organelles, whereas the ZnT family exports zinc from the cytosol to organelles or out of the cell 15,30

TDP-43 pathology was originally defined with the accumulation of proteins that include phosphorylated TDP-43 (pTDP-43) in the cytoplasm of neurons that undergo degeneration 10 , and this pathology was broadly observed in a wide spectrum of ALS cases 44

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