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137 In metastatic CRPC, coloss of TP53/RB1 and overexpression of SOX2 activate JAK1/STAT1, promoting lineage plasticity and transition to a stem-like, multilineage-resistant state

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As a tripeptide, it is rapidly cleaved by serum and tissue peptidases into its constituent amino acids (glycine, histidine, lysine) and free copper(II) ions 3

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