Immune regulation
Relevant brain areas implicated in GLP-1 control of body weight and food intake include the the hypothalamic arcuate nucleus 57,58,59 and the hindbrain DVC 59,60 , hence the same brain regions that are targeted by long-acting GIPR agonists 15,20,21
triagonism) on energy expenditure, glucose regulation, food intake, and weight loss in a well-established DIO mouse model in comparison to clinically relevant GLP1 receptor agonists [83]
But in other organs, the number of immune cells containing GLP-1 receptors is negligible, indicating another mechanism to be at play
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PMID 11419954