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DSIP is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) studied in sleep and neuroregulatory research
Sampedros team (Sampedro et al., 2019) discovered in mice that treatment with GLP-1RAs resulted in a significant decrease in VEGF levels in the retina, kidneys, and systemic circulation
Evidence strength: Low direct evidence
Sports and athletics: DSIP is not specifically listed on the WADA prohibited substances list, but given its potential to enhance recovery, future regulatory attention is possible
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Conversations around peptides often include: Some peptides target metabolic pathways, while others support cellular repair or tissue function
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