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Clinical trials of IGF-1 in multiple sclerosis (MS), ALS, Parkinsons disease (PD), and Alzheimers disease (AD) have yielded mixed results
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This has the effect of lowering blood sugar
In people with type 2 diabetes at high cardiovascular risk, 104 weeks of treatment with tirzepatide was associated with reduced albuminuria and a slower decline in eGFR compared with treatment with insulin glargine
Large-scale trials including SUSTAIN-6 have demonstrated cardiovascular benefits and reduced major adverse cardiovascular events in high-risk patients
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