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1), and the first GLP-1 analogue brought into clinical development was liraglutide, a once-daily injection
They aren't simple, robust chemical compounds
In cases requiring more intensive glucose control, insulin therapy remains an effective option, though it requires more frequent monitoring and carries a risk of hypoglycaemia and weight gain
This is a crucial reason why a specialist should prescribe these drugs
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Wegovy carries an additional indication for cardiovascular risk reduction in adults with obesity and established cardiovascular disease, based on outcomes from the SELECT trial
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