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DPP-4 Inhibitors and BP Regulation: Potential Mechanisms Primary hypertension is a cardiovascular syndrome characterized by elevated BP, and represents the leading cause of cardiovascular disease and stroke and the primary cause of death and disease burden worldwide ( Immunological Mechanisms of DPP-4i Upon Hypertension Many chronic diseases are closely related to non-specific inflammatory processes, such as insulin resistance, metabolic syndrome, T2DM, and coronary heart disease, which are associated with increased infiltration and cell proliferation of immune cells and the elevated release of inflammatory mediators
Modifiable risk factors, such as being overweight, having disrupted glucose regulation, hypertension, and dyslipidaemia, are significant contributors to the beginning and development of CVDs (72)
Antioxidant Power It helps neutralize free radicals, which can damage cells and contribute to aging, cancer, and other diseases
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37, 23622380, e2368
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