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Allodynia represents a neurological misfiring where your central nervous system has, temporarily, lost the ability to correctly categorize incoming sensory data

Last reviewed: June 19, 2026 Last updated: June 19, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Large randomized controlled trialsincluding the STEP program, which evaluated over 4,500 patientsestablished that semaglutide at doses between 0.5 mg and 2.4 mg weekly produces weight loss of 1022% body weight reduction and improves cardiovascular risk markers like blood pressure and cholesterol