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The peptide GLP-1 is produced by the enteroendocrine L-cells of the small intestine as a cleavage product of the pre-proglucagon gene within minutes in response to oral glucose or fat
10.3390/antiox11122345 69 NikpayamO.RouhaniM
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Thus, in the course of aging various potentially pathogenic mechanisms, including the increase in oxidative damage, could on the one hand influence the quality of aging and on the other favour the onset and evolution of a definite neurodegenerative disease
Additionally, certain medications (including some antipsychotics, antidepressants, and corticosteroids) and endocrine conditions can contribute to increased appetite and food preoccupation
These are the side effects that occur frequently, typically resolve on their own or with minor adjustments, and rarely require stopping the peptide entirely
