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Starting with genetic insights often saves patients time and money by matching them to their optimal compound on the first try

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Because it hits multiple melanocortin receptor types, it also affects appetite and sexual desire

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FIGURE 2 TABLE 1 Characteristics of Urate transporters

(Exenatide is FDA approved as monotherapy for the management of T2DM.) Explicitly stated in the guideline for patients requiring dual or triple therapy, the AACE/ACE preferentially recommends the addition of a GLP-1 receptor agonist or a DPP-4 inhibitor (sitagliptin, saxagliptin), citing their efficacy and safety profiles as preferred agents over TZDs or sulfonylureas (SUs)