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Proper preparation and technique can minimize these reactions and ensure a smoother experience

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Constipation: This is reported slightly more often with semaglutide, at 29% versus 27% with tirzepatide

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Structural modifications protect against DPP-4 degradation and extend the peptides half-life, allowing once-weekly dosing Pancreas: Enhanced glucose-dependent insulin secretion

It is preferable not to combine it at the beginning of use with several strong products containing exfoliating acids or retinol if the skin is sensitive or easily irritated