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The SWI/SNF (BAF) complex, an ATP-dependent chromatin remodeling complex in the nucleus that endows DNA with the capacity for replication and enables selective gene expression and DNA repair and recombination, is frequently mutated in human cancers and thus exerts a great impact on tumorigenesis 51

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(3) 1000 mg metformin at t = 0 min and 0.9% saline at t = 60 and 30 min [Met (0 min)]