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Jin, X.-W., Liu, B.-K., Zhang, X., Zhao, Z.-H

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Standard therapies are often applied based on the general diagnosis, without clearly determining which anatomical structure is responsible for the pain, what pathological process is occurring within that structure, and which contributing factors are maintaining the pain and it is precisely this failure to identify all three that leads to persistent pain despite treatment

To interrogate the potential effect of the lipidation on the Cagri-bound structures, we also determined structures of the CTR and AMY 1 R bound to a Cagri analogue lacking the N-terminal lipidation (CagriBB)

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