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DOI Bossart M, Wagner M, Elvert R, et al
Uric acid and hypertension
A sweeping meta-analysis in The Lancet Diabetes & Endocrinology pooled data from 11 large trials and over 85,000 participants and found that GLP-1 therapies reduced the risk of kidney failure by 16%, slowed significant declines in filtration rate by 22%, and lowered the combined risk of dialysis, severe loss of function, or kidney-related death by 19%
Since the approval of exenatide for the treatment of type 2 diabetes by the Food and Drug Administration (FDA) in 2005, research on GLP-1 RAs has become a hot topic and new analogs are constantly being introduced to the market
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