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the lack of a control group in that trial may lead to inaccurate conclusions

Then, they evaluated the permeability for the BBB of the liposomes to confirm the role of transferrin, and the behaviors of cellular internalization and lysosomal escape to confirm the role of CPP

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The cumulative effect of these factors - protection from digestive degradation, improved cellular uptake, sustained release, and reduced first-pass metabolism - is significantly enhanced bioavailability

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