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PubMed Central PMCID: PMC125592
The trial demonstrated dose-dependent weight loss, with participants receiving 12 mg achieving a mean body weight reduction of approximately 24% over 48 weeks a result that has attracted considerable scientific and public interest
The gastrointestinal effects of the medication are well-documented in the SmPC and European Public Assessment Report (EPAR), but hiccups specifically have not been validated through controlled clinical studies
It mimics the action of amylin, a hormone that plays a distinct but complementary role in appetite control and energy regulation
