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This article focuses on what the peer-reviewed literature actually reports about the side effects and tolerability of GHK-Cu

They focus on the overall experience of the patient, blending reported symptoms with medical evaluation

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[50] Hypopigmentation or hyperpigmentation at the application site has been reported with azelaic acid use, though these pigmentary changes are typically reversible upon discontinuation and may actually represent a beneficial effect in patients with post-inflammatory hyperpigmentation