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Patients with higher baseline insulin resistance or persistent metabolic dysfunction may benefit from more intensive monitoring and structured intervention during discontinuation
The Phase 2 data proved that starting higher doubles GI side effects with no benefit to long-term outcomes
Cardiovascular benefits: Clinical trials have demonstrated that tirzepatide can reduce the risk of major adverse cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who have established cardiovascular disease
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Biol Reprod 71:10021008
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