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It will also explore the latest links with metabolic syndromes, hormonal imbalances associated with ageing and targeting of IGF signalling in endocrine-related tumour growth with an emphasis on post-menopausal breast cancer and the impact of the steroidal milieu
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Moreover, given that AD has been described as type 3 diabetes, with evidence suggesting peripheral metabolic dysfunction may play a role in disease initiation and progression (similar to the peripheral-to-central spread proposed in Parkinsons disease), blood transcriptomic analysis offers a relevant and practical window into the early disease mechanisms we sought to evaluate
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