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Critically, sophisticated EEG analysis confirmed no sedation in the classical pharmacological sense establishing that DSIP sustains natural sleep functions rather than inducing pharmacological sedation

J Physiol Pharmacol Off J Pol Physiol Soc

If a day is missed, the research-sensible response is simply to resume the next scheduled dose, not to double up, because there is no acute deficit to make good and doubling only departs from the documented figure

Neurosci Biobehav Rev 8:8393