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Dig Liver Dis (2010) 42(5):32030
Further studies in Per2Luc knock-in mice revealed that chronic light-dark disruption elevated pro-inflammatory cytokines (e.g., IL1, IL6, GM-CSF) and impaired host resilience to endotoxin challenge 126
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Supports Hormone Balance & Autoimmune Conditions GLP-1s can help regulate hormones like insulin and leptin, but LDN goes deeper by calming the root-level immune dysfunction that drives many hormonal imbalances, especially in autoimmune-related weight gain (e.g., Hashimotos)
Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohns disease
This protective association has been repeatedly observed, linking GLP-1RA use to lower risks of POAG, ocular hypertension, and the need for first-line glaucoma treatment in large cohorts of T2DM patients [105,106,107]
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