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The metabolic benefits of GLP-1 therapy extend well beyond weight loss, including beta-cell preservation, improved insulin sensitivity, and cardiovascular risk reduction
Mol Psychiatry 27:50495061 Bot M, Milaneschi Y, Al-Shehri T, Amin N, Garmaeva S, Onderwater GLJ, Pool R, Thesing CS, Vijfhuizen LS, Vogelzangs N, Arts ICW, Demirkan A, van Duijn C, van Greevenbroek M, van der Kallen CJH, Kohler S, Ligthart L, van den Maagdenberg A, Mook-Kanamori DO, de Mutsert R, Tiemeier H, Schram MT, Stehouwer CDA, Terwindt GM, Willems van Dijk K, Fu J, Zhernakova A, Beekman M, Slagboom PE, Boomsma DI, Penninx B, Consortium B-NM (2020) Metabolomics profile in depression: a pooled analysis of 230 metabolic markers in 5283 cases with depression and 10,145 controls
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Several factors can influence how quickly youll experience benefits: Initial B12 Levels Those with severe deficiencies may notice more dramatic and rapid improvements compared to those with mild deficiencies
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We are likely to continue to see clinical trials include treatment of adiposity-related diseases as a component of obesity medication investigations
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